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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New treatments for hair loss may target specific pathways and generate new hair follicles.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

A new 3D culture system helps grow and study mouse skin stem cells for a long time.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

Immune cells are essential for early hair and skin development and healing.

ILK is essential for skin development, pigmentation, and healing.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

MED1 affects skin wound healing differently in young and old mice.

CD61 is important for mouse tooth cell growth and works through Lgr5.

A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.