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    Glossary RSPO3

    protein involved in hair follicle development and regeneration

    RSPO3 stands for R-spondin 3, a protein that plays a crucial role in the Wnt signaling pathway, which is important for cell growth and development. In the context of hair biology, RSPO3 is involved in the regulation of hair follicle development and regeneration, making it a significant factor in understanding conditions like alopecia.

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    Research 10 of 138

    1. H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development Epigenetics & Chromatin · 2025 · 1 citations
    2. RSPO1-mutated keratinocytes from palmoplantar keratoderma display impaired differentiation, alteration of cell–cell adhesion, EMT-like phenotype and invasiveness properties: implications for squamous cell carcinoma susceptibility in patients with 46XX disorder of sexual development Orphanet journal of rare diseases · 2022 · 5 citations
    3. RSPO1, a potent inducer of pancreatic β cell neogenesis Cell Reports Medicine · 2025 · 1 citations
    4. Management of a Refractory EIF3E-RSPO2 Fusion Positive Pilomatrical Cancer Patient with Encyclopedic Tumor Analysis Guided Treatment Acta Scientific Cancer Biology · 2020
    5. Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells Frontiers in Cell and Developmental Biology · 2020 · 8 citations
    6. The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells Frontiers in Physiology · 2024 · 6 citations
    7. High-throughput screening of small molecule Wnt/β-catenin activators for hair and nail growth Communications Biology · 2026
    8. High-Throughput Screening for Discovering Small Molecules Capable of Increasing the Wnt/β-Catenin Signaling Pathway to Promote Hair and Nail Growth Research Square (Research Square) · 2024
    9. 189 Integrating single-cell and spatial transcriptomics of human hair follicles to define transcriptional signature of follicular dermal papilla 2022
    10. Characterizing the cellular diversity and molecular signatures within the hair follicle dermal stem cell lineage PRISM (University of Calgary) · 2017
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