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The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

Targeting and modifying the stem cell niche can improve regenerative therapies.

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Researchers found 617 genes that behave differently in cashmere goat hair follicles, which could help understand hair growth.

Many survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo suffer long-term eye and skin problems.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.

Regenerative medicine may help reduce radiotherapy side effects like skin cancer, fibrosis, pain, and hair loss.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Caffeine can protect scalp hair follicles from damage caused by UV radiation.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

No clear link between hair loss and metabolic syndrome, but some differences in blood pressure and glucose levels.

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.

The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.

Sebaceous glands are often preserved and PPARy expression is constant in some cases of Central Centrifugal Cicatricial Alopecia.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The circadian clock influences the behavior and regeneration of stem cells in the body.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.