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Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

TGFβ signaling prevents sebaceous gland cells from producing fats.

The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

A specific RNA molecule blocks hair growth by affecting a protein related to hair loss conditions.

PPAR alpha may help in hair growth and could be a target for treatment.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

Different types of stem cells in the skin contribute to the variety of melanoma forms.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Melatonin improved mental health and metabolism in women with PCOS.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

The research identified key proteins and genes that may influence wool bending in goats.

Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.

Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.

New culture method keeps human skin stem cells more stem-like.

A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Glucosylceramides are essential for healthy skin and proper wound healing.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.