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    Non-Hormonal Treatment Options for Regulation of Menstrual Cycle in Adolescents with PCOS

    December 2022 in “ Journal of Clinical Medicine ”
    Elisabeth Reiser, Julia Lanbach, Bettina Böttcher, Bettina Toth
    Studysummary This review suggests that, among non-hormonal treatments for menstrual irregularities in adolescents with PCOS, metformin is the most effective and cost-efficient option, particularly in overweight adolescent girls.
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    Research cited in this study 7

    1. Criteria for Diagnosis of Polycystic Ovary Syndrome During Adolescence: Literature Review Diagnostics · 2022
    2. The Possibilities of Using Chromium Salts as an Agent Supporting Treatment of Polycystic Ovary Syndrome Biological Trace Element Research · 2019
    3. A 12-Week Treatment with the Long-Acting Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Leads to Significant Weight Loss in a Subset of Obese Women with Newly Diagnosed Polycystic Ovary Syndrome Hormones · 2015
    4. Intermittent Low-Dose Finasteride Administration Is Effective for Treatment of Hirsutism in Adolescent Girls: A Pilot Study Journal of Pediatric and Adolescent Gynecology · 2014
    5. Short-Term Combined Treatment With Liraglutide and Metformin Leads to Significant Weight Loss in Obese Women With Polycystic Ovary Syndrome and Previous Poor Response to Metformin European journal of endocrinology · 2013
    6. Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study The Journal of Clinical Endocrinology and Metabolism · 2013
    7. Intermittent Low-Dose Finasteride Is as Effective as Daily Administration for the Treatment of Hirsute Women Fertility and Sterility · 2004