Metabolic Syndrome – A New Definition and Management Guidelines: A Joint Position Paper by Various Polish Medical Societies
August 2022
in “
Archives of Medical Science
”
obesity hypertension carbohydrate metabolism lipid metabolism high blood pressure impaired glucose metabolism non-HDL cholesterol lifestyle modifications orlistat bupropion hydrochloride naltrexone hydrochloride GLP-1RA bariatric surgery BMI type 2 diabetes mellitus obstructive sleep apnoea polycystic ovary syndrome hyperuricaemia sympathetic overdrive tachycardia inflammation lifestyle changes Xenical Contrave GLP-1 receptor agonist weight loss surgery body mass index type 2 diabetes sleep apnea PCOS high uric acid fast heart rate
TLDR The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.
The joint position paper by various Polish medical societies provides a new definition and management guidelines for metabolic syndrome (MetS), a health issue characterized by obesity, hypertension, and disordered carbohydrate and lipid metabolism. The new definition includes obesity and two of the following criteria: high blood pressure, impaired glucose metabolism, or elevated non-HDL cholesterol level. The paper emphasizes lifestyle modifications as key interventions for prevention and treatment of MetS, but also suggests medical management, including drugs like orlistat, bupropion hydrochloride, naltrexone hydrochloride, and GLP-1RA, when non-medical interventions prove ineffective. Bariatric surgery is recommended for patients with a BMI > 40 kg/m2, those with a BMI of 35–39.9 kg/m2 and ≥ 1 obesity-related disease, and those with a BMI of 30–35 kg/m2 and uncontrolled type 2 diabetes mellitus. The paper also discusses the management of related conditions such as obstructive sleep apnoea, polycystic ovary syndrome, hyperuricaemia, sympathetic overdrive and tachycardia, and inflammation.
