22 citations,
June 2005 in “Clinical Oncology” Orlistat might block the body's ability to absorb thyroid medication.
4 citations,
January 2018 in “JBRA assisted reproduction” Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
February 2020 in “Scholars academic journal of pharmacy” The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.
70 citations,
April 2013 in “Endocrine” Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
38 citations,
January 2011 in “Endocrine Journal” Weight loss and metformin don't significantly change vaspin levels in women with PCOS.