January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
October 2022 in “Cosmoderma” 489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
March 2023 in “Anais Brasileiros De Dermatologia” Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.
52 citations,
January 2022 in “Current Research in Pharmacology and Drug Discovery” New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.
2 citations,
September 2022 in “American Journal of Clinical Dermatology” 2 citations,
April 2002 in “Animal Science/Animal science” Melatonin treatment speeds up fur maturation and changes the hair growth cycle in young chinchillas.
10 citations,
January 2014 in “Genetics and Molecular Research” Liaoning Cashmere goat hair follicles show synchronized growth patterns with lowest activity in May.
5 citations,
November 2015 in “International Journal of Radiation Biology” Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
9 citations,
January 2010 in “International Journal of Trichology” The study found that the cause of alopecia areata can be identified through tissue analysis, and vertical sections are enough for diagnosis.
15 citations,
January 2015 in “Pharmaceutical Biology” Chrysanthemum zawadskii extract may be a better treatment for hair loss than Minoxidil.
8 citations,
January 2021 in “Pharmaceutics” Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.
10 citations,
May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
4 citations,
June 2020 in “British Journal of Pharmacology” Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.
81 citations,
February 1997 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by activating PGHS-1.
4 citations,
July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
6 citations,
February 2022 in “JAAD International” Higher doses of isotretinoin may lead to more hair loss.
46 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
9 citations,
January 2014 in “DARU Journal of Pharmaceutical Sciences” Cuscuta reflexa extracts helped regrow hair in rats with drug-induced hair loss.
18 citations,
April 2021 in “Experimental Dermatology” COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
21 citations,
November 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Telogen is an active phase with important biological processes, not a resting phase.
41 citations,
June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
34 citations,
June 1990 in “British Journal of Dermatology” Etretinate treatment changed hair growth patterns in many patients.
January 2015 in “Journal of clinical and investigative dermatology” Clipping is the best method to prepare rats for studying hair loss from chemotherapy because it causes less skin damage and effectively gets hair to the right growth phase.
211 citations,
October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
14 citations,
January 2017 in “Pharmacological Reports” TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
2 citations,
December 2013 in “Xenobiotica” Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
15 citations,
May 2020 in “BMC complementary medicine and therapies” Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
11 citations,
April 2013 in “Journal of Proteomics” Found different proteins in balding and non-balding cells, giving insight into hair loss causes.