The Effect of Amniotic Fluid on Hair Follicle Growth

September 2023 in “ bioRxiv (Cold Spring Harbor Laboratory) ”

Gamze Tumentemur, Elif Ganime Aygün, Bulut Yurtsever, Didem Çakırsoy, Ercüment Ovalı

amniotic fluid freezing amniotic fluid gamma-irradiated amniotic fluid hair follicle growth anagen phase arginase+1 CD68 human amniotic fluid FAF FAFI

TLDR Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.

The study investigated the effects of freezing amniotic fluid (FAF) and freezing gamma-irradiated amniotic fluid (FAFI) on hair follicle growth in a rat hair loss model. Results indicated that both FAF and FAFI increased the total number of hair follicles and accelerated the transition to the anagen (growth) phase. Additionally, there was an increased rate of arginase+1 (Arg+1)/CD68 activity around hair follicles treated with human amniotic fluid. The findings suggest that FAFI, in particular, may be a safe and effective treatment for promoting hair follicle growth and accelerating the anagen phase in hair loss conditions.

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