2 citations
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November 2021 in “International Journal of Applied Pharmaceutics” This study found that a phytosome lotion made from Mangkokan leaf extract, using a green solvent and microwave-assisted extraction, demonstrated greater hair growth activity than 2% minoxidil, with the 30% phytosome lotion showing the highest efficacy in increasing hair length, weight, and diameter.
This study concluded that bitter melon leaf ethanol extract can be effectively formulated into a shampoo that meets quality standards and promotes rabbit hair growth.
February 2020 in “Phytotherapy Research” This article discusses the clinical evaluation of pea sprout extract for treating hair loss but reports no new research findings.
5 citations
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June 2018 in “Records of Natural Products” This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.
This study found that the Padina arborescens extract and its component MOGG may prevent hair loss by inhibiting 5α-reductase activity, promoting cell proliferation, opening the KATP channel, and increasing PGE2 production in laboratory settings.
September 2024 in “Sasambo Journal of Pharmacy” This study formulated and tested a pomegranate leaf shampoo with antifungal properties, identifying an optimal composition of 5.5% SLS and 15.5% cocamide DEA, showing good foam stability, appropriate pH, and viscosity in lab tests.
This study found that a 10% hibiscus leaf extract hair tonic demonstrated better hair growth activity than 2% minoxidil in rabbits but caused eye irritation.
22 citations
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February 2018 in “International Journal of Pharmacy and Pharmaceutical Sciences” This review compiles existing research on Peperomia pellucida's traditional medicinal uses and pharmacological properties but reports no new findings, suggesting its potential for drug development.
June 2022 in “International Journal for Research in Applied Science and Engineering Technology” The research developed a herbal shampoo using extracts from Piper Betel and Psidium Guajava leaves, which showed potential in promoting hair growth and managing hair diseases, while replacing synthetic ingredients with safe natural alternatives.
January 2025 in “Bandung Conference Series Pharmacy” This study found that a solid shampoo containing 15% tin leaf extract (Ficus carica L.) and 1% vitamin E exhibited strong antioxidant activity, with a 53.43% inhibition of free radicals in hair and scalp, suggesting potential for reducing hair loss and premature aging.
3 citations
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December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
4 citations
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August 2023 in “Journal of Cosmetic Dermatology” Gynostemma pentaphyllum extract may help grow hair and prevent graying.
January 2024 in “Biological & pharmaceutical bulletin” In this study, Panax ginseng extract and its ginsenosides were found to stimulate the proliferation of hair-related cells and promote the transition from the telogen to the anagen phase, enhancing hair-shaft growth by suppressing BMP4 expression in human dermal papilla cells.
20 citations
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August 2015 in “International Journal of Molecular Medicine” This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.
2 citations
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March 2022 in “Applied sciences” In this study, Lespedeza bicolor extract was found to enhance dermal papilla cell proliferation and extend the anagen phase in mice, suggesting its potential as a treatment for alopecia.
This study focused on extracting compounds from curry leaves using various methods and evaluated the extract's purity, solubility, and stability, suggesting potential health benefits like improved digestion and hair growth.
December 2024 in “Tropical Journal of Natural Product Research” This study evaluated the anti-alopecia effects of Petroselinum crispum leaf extracts in a rabbit model and through molecular docking analysis, finding that two ethyl acetate fractions promoted hair growth, with effects comparable to minoxidil, suggesting potential for alopecia treatment development.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” In this experimental study on rabbits, the authors concluded that a pomade containing 10% meniran leaf extract was an effective hair growth stimulant and could compete with a positive control, fulfilling the required pomade characteristics.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
This study found that pectin lyase-modified red ginseng extract (GS-E3D) may promote hair growth by enhancing antioxidant and anti-inflammatory effects, proliferating hair dermal papilla cells, and inhibiting 5α-reductase activity.
September 2025 in “Molecules” This study found that Camellia oleifera leaf extracts, especially the 50% ethanolic extract, have significant antioxidant activity and may offer promising bioactive compounds for cosmetic and pharmaceutical uses.
September 2020 in “Himalayan Journal of Health Sciences” This review summarizes the diverse pharmacological activities of papaya leaf extract, highlighting its strong medicinal properties and potential cosmetic applications, but reports no new clinical results.
December 2022 in “Journal of applied biological chemistry” In this study, Betula platyphylla extract, particularly fraction H3-2, promoted human derma papilla cell proliferation and increased expression of certain growth factors, suggesting potential benefits for hair loss prevention.
This study found that gels containing glycyrrhizic acid and aqueous Glycyrrhiza glabra extract significantly reduced underarm hair growth in terms of area, thickness, length, and number compared to their gel bases.
April 2021 in “Journal of Investigative Dermatology” This study suggests that edelweiss extract may promote hair growth and reduce shedding in ex vivo experiments by affecting hair follicle anagen phase duration and keratinocyte proliferation.
This study found that ethanolic plant extract of Peperomia pellucida increased hair length in rabbits in a dose-dependent manner but did not significantly affect hair mass compared to controls.
April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
January 2025 in “Termometer Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran” In this study, researchers tested a tea leaf ethanol extract (Camellia sinensis) hair tonic and found it increased average hair growth compared to positive and negative controls over 28 days, but exhibited some instability and inhomogeneity after accelerated testing.
This study found that olive leaves extract significantly decreased prostate index, serum PSA, testosterone, and DHT levels in male rats with testosterone-induced benign prostatic hyperplasia, and showed potential as a therapeutic option due to its positive effects on prostate histology and antioxidant activity.
1 citations
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April 2017 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study found that the combination of Pandan Wangi leaves and Noni fruit extracts may inhibit fungi commonly associated with dandruff, suggesting potential use in anti-dandruff shampoo formulations.