March 2024 in “Journal of Pharmaceutical and Sciences” This study investigated the phytochemical composition and antibacterial and antioxidant activities of Zaleya pentandra extracts, finding high total polyphenol and flavonoid content and significant antibacterial effects, particularly in acetone extract, which may be suitable for developing antibacterial agents.
December 2023 in “Sains Malaysiana” In this study, researchers used in silico mutagenesis to identify key calcium-binding sites influencing the stability of Rand protease from Bacillus subtilis, potentially enhancing its application in industries like leather dehairing by improving stability and eliminating the need for additional metal ions during the process.
November 2023 in “Manuju” This paper discusses the complex relationship between polycystic ovary syndrome (PCOS) and hyperprolactinemia, noting a decrease in prolactin levels following bromocriptine treatment, but reports no new clinical findings.
October 2023 in “Al-Kauniyah” In this study of gibbons at the Tegal Alur Animal Rescue Center, researchers found that while the feeding schedule met natural requirements, the gibbons' body weights were lower compared to their counterparts in the wild, and some exhibited hair loss and depigmentation.
September 2023 in “Jurnal MIPA (edisi elektronik)” This study formulated and evaluated the physical stability of hair tonic preparations using lime extract (Citrus aurantifolia) at varying concentrations. The researchers found that the tonics exhibited good physical stability, as indicated by meeting Indonesian National Standards, even after undergoing temperature cycling tests.
This study found that varying the concentration of propylene glycol in katuk leaf extract hair tonic formulations significantly affects the viscosity, highlighting the importance of propylene glycol concentration in maintaining the physical characteristics of these preparations.
June 2023 in “Sains Malaysiana” This study evaluated the effectiveness and safety of a cinchonine nanostructured lipid carrier serum for hair growth in mouse models, finding that it significantly increased hair length and enhanced follicle penetration compared to controls, with no notable irritation observed.
May 2023 in “Jurnal Sains Insani” This study focused on Shaykh Abbas Kuta Karang, a prominent 19th-century Malay scholar, and his influential medical manuscript, Al-Rahmah fi al-Tib wa al-Hikmah, which documents traditional Malay medical knowledge spanning human anatomy, dietary principles, and treatments for various illnesses.
January 2023 in “Biocell” The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.
December 2022 in “Jurnal Kesehatan Jompa” This article reviews the causes and current treatment options for androgenetic alopecia, reporting no new clinical findings and highlighting the need for more therapeutic choices.
August 2022 in “FAKUMI MEDICAL JOURNAL Jurnal Mahasiswa Kedokteran” This study found no significant effect of dandruff on the severity of androgenic alopecia compared to cases without dandruff.
January 2022 in “Healthy Tadulako Journal” This study found no difference in the physical stability of hair tonic preparations made from sansevieria leaves extract, regardless of whether maceration or soxhletation methods were used.
January 2022 in “JPK Jurnal Proteksi Kesehatan” This study found that the ethanol extract of mangkokan leaf (Polyscias scutellarium) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with higher concentrations showing greater inhibition zones, particularly against Staphylococcus aureus.
December 2021 in “Jurnal ilmiah Manuntung” This study tested a hair tonic containing gotu kola and garlic extracts on rabbits, finding that the formulation with 5% gotu kola and 0.04% garlic showed promising hair growth results and remained stable during storage.
December 2021 in “Bandung Conference Series. Pharmacy” This literature review found that combinations of certain herbal extracts with coconut oil, such as Hibiscus rosa sinensis and Centella asiatica, promoted hair growth in animals over 30 days, with varied results across rat and rabbit models.
June 2021 in “Current Biochemistry” This study determined that a 6.25% concentration of propolis effectively inhibits the growth of dandruff-causing bacteria, with effectiveness values of 223.52% and 99.59% compared to ketoconazole and another propolis extract, respectively.
In this study, a hair tonic formulation with bean leaf juice increased hair growth in male rabbits, with concentration-dependent improvements in hair length and weight compared to a control.
November 2018 in “Klinická farmakologie a farmacie” Alopecia in young women improves with effective treatment.
In this case report, combination therapy with topical tretinoin, topical and intralesional steroids, and systemic doxycycline showed improvement in AKN lesions for a 19-year-old man, with notable reductions in lesion size and number observed by the second week.
November 2016 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)” This study found that Dendrobium sabin flower extracts, especially the methanolic one, demonstrated strong antioxidant and anti-aging properties without significant toxicity, suggesting its potential in treating photo-induced skin aging.
February 2015 in “Jurnal e-Biomedik” This study found that aloe vera extract accelerated wound healing in incised rabbit skin.
December 2014 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This case report describes successful treatment of a four-year-old boy with kerion-type tinea capitis caused by T. mentagrophytes using griseofulvin, erythromycin, wet dressing, and ketokonazole shampoo, with improvement after 8 weeks.
April 2014 in “Jurnal Biomedik : JBM” This case report diagnosed an 8-year-old girl with trachyonychia and secondary onychomycosis, finding that spontaneous improvement is common, making specific therapy often unnecessary despite treatment challenges with associated fungal infections.
July 2012 in “Ubaya Repository (University of Surabaya)” This study found that hair growth gel and tonic containing red grape seed extract were physically and chemically unstable under high temperature and humidity conditions over 30 days.
134 citations
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January 2011 in “Development” This study found that disrupting Adam10 in the epidermis led to severe skin and multi-organ abnormalities, implicating Adam10 as crucial for proper Notch signaling and skin maintenance.
111 citations
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March 2012 in “Expert Opinion on Drug Delivery” This review discusses the potential use of liposomal formulations to enhance the effectiveness of cosmeceutical delivery through the skin barrier, with no new clinical results reported.
77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
61 citations
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May 2015 in “Planta” Certain fungi and bacteria help orchid seeds germinate and plants grow better.
40 citations
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July 2013 in “Skin Pharmacology and Physiology” This study reports that among men, skin surface hydration and pH change with age, but transepidermal water loss and sebum production show less variation.
17 citations
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July 2018 in “International Journal of Cosmetic Science” This study found that keratin-based particles were able to recover and enhance the mechanical properties and thermal stability of virgin and overbleached Asian hair, improving its strength and smoothness by around 40%, and demonstrated safety in human skin keratinocytes.