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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

More research is needed to determine if iron deficiency causes hair loss.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Smoking and drinking worsened hair loss in men with genetic hair loss, while eating and sleeping habits didn't; genetics played a bigger role than environment in hair loss.

Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

Genetic factors alone might not cause pemphigus vulgaris; other factors like birth complications and puberty may trigger it.

Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.

COVID-19 may harm male fertility and damage the reproductive system.

Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.