Androgens and Erythropoiesis: Induction of Erythropoietin-Hypersecretory State and Effect of Finasteride on Erythropoietin Secretion

March 1999 in “ Comparative Haematology International ”

A. C. Barceló, María I. Olivera, Clarisa Bozzini, Rosa M. Alippi, Clarisa Bozzini

androgens erythropoiesis erythropoietin EPO finasteride Propecia

TLDR Androgens increase EPO production, finasteride doesn't significantly impact it.

This paper discusses the relationship between androgens and erythropoiesis, specifically the production of erythropoietin (EPO) and the impact of finasteride on EPO secretion. The study found that androgens can increase EPO production, leading to an EPO-hypersecretory state, while finasteride does not have a significant impact on EPO secretion. The paper suggests that androgens may have therapeutic uses in hematologic conditions, and finasteride may have unintended effects on erythropoiesis.