2 citations
,
January 2025 in “International Journal of Molecular Sciences” This study found that chitosan nanoparticles containing Cordyceps militaris effectively reduced lung damage in mice exposed to fine particulate matter (PM2.5) by decreasing oxidative stress and preserving lung barrier integrity, suggesting potential as a therapeutic candidate for PM2.5-induced lung diseases.
27 citations
,
September 1999 in “Journal of Investigative Dermatology” This study found that protease nexin-1 mRNA is expressed in human dermal papilla cells and is downregulated by dihydrotestosterone in balding scalp, suggesting a role in male-pattern baldness progression.
215 citations
,
January 2011 in “Reproductive Biology and Endocrinology” Among reproductive-aged women in Iran, this study found that the prevalence of PCOS varied significantly depending on the diagnostic criteria used, with estimates ranging from 7.1% to 14.6%.
2 citations
,
December 2023 in “Current Pharmaceutical Biotechnology” This review discusses the potential of novel delivery systems to improve the bioavailability and therapeutic effects of herbal bioactives in colorectal cancer treatment.
14 citations
,
May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
2 citations
,
December 2021 in “Cureus” This study found that cutaneous manifestations are prevalent in PCOS patients, with 68% experiencing symptoms like hirsutism and acne, highlighting the need for better awareness across medical specialties.
15 citations
,
February 2023 in “Colloids and surfaces. B, Biointerfaces” In this study using a porcine skin model, the researchers reported that smaller curcumin nanocrystals in xanthan gum gel showed higher passive skin penetration, while larger particles achieved deeper follicular accumulation.
53 citations
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November 2021 in “Molecular Human Reproduction” This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.
June 2020 in “Research Square (Research Square)” This study found that oral contraceptives containing cyproterone acetate significantly improved the overall quality of life in polycystic ovary syndrome patients after six months, compared to those containing levonorgestrel.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Ashwagandha-derived nanovesicles increased cell proliferation, angiogenesis, and growth factor expression in vitro, suggesting they may have potential as a plant-based alternative or complement to current therapies for hair and skin conditions.
26 citations
,
February 1978 in “Journal of Pediatric Surgery” This study found that long-term total parenteral nutrition in pediatric patients led to severe zinc deficiency, which improved with intravenous zinc therapy, highlighting the need for adequate zinc inclusion in nutritional solutions.
7 citations
,
January 2016 in “Methods in molecular biology” This report introduces a tissue-engineered nerve conduit combining hfNCSCs-derived neurons and acellular nerve grafts to potentially repair long-distance peripheral nerve injuries.
September 2025 in “Global Journal of Pharmacy & Pharmaceutical Sciences” This review analyzes PDRN's molecular mechanisms and therapeutic applications in anti-aging dermatology but reports no new clinical results, highlighting the need for more standardized protocols and long-term evaluations.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews existing strategies for managing polycystic ovarian disease and highlights the role of lifestyle changes, natural remedies, and conventional treatments, reporting no new clinical results.
August 2018 in “Ayurlog: national journal of research in ayurveda science” This study reviewed Ayurvedic and modern texts to identify methods for managing PCOD through Ayurvedic dietary practices, proposing that these may help address symptoms by improving metabolic and endocrine functions without specific experimental results reported.
June 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” This study observed that a significant proportion of women with acne vulgaris also met the criteria for PCOS, suggesting a notable link between the two conditions.
In this study, introducing the rat OTC gene into spf-ash mice led to increased OTC activity and normalized hair growth and biochemical markers like urinary orotic acid and serum citrulline, partially correcting the symptoms of OTC deficiency.
February 2025 in “Archives of Dermatological Research” Polynucleotides effectively promote hair regrowth in androgenetic alopecia without serious side effects.
March 2024 in “ACS Applied Materials & Interfaces” This study developed a delivery platform using hyaluronic acid-based dissolvable microneedles with nanoliposomes containing kopexil and kopyrrol, which showed improved hair regeneration for treating androgenetic alopecia in vivo at lower dosages compared to minoxidil.
3 citations
,
April 2017 in “Journal of Medical Science And clinical Research” In this study, acne was the most common skin manifestation among women with PCOS, significantly correlated with elevated LH levels and the LH:FSH ratio.
2 citations
,
April 2024 in “Cosmetics” This study investigated non-laser methods for removing permanent makeup using plant extracts, testing their decolorization effects on mice through tattooing and electroporation techniques.
30 citations
,
July 2009 in “Experimental and clinical endocrinology & diabetes” This article reviews the use of cyproterone acetate for conditions like prostate cancer and sexual disorders, highlighting its effects on libido but reporting no new specific trial results.
1 citations
,
December 2025 in “Inorganics” This review analyzes the role of silver nanoparticles in wound healing, highlighting their antimicrobial, anti-inflammatory, and tissue-regenerating properties, and emphasizes the need for further research to optimize formulations and ensure safety.
39 citations
,
January 2006 in “Journal of Cosmetic and Laser Therapy” This study found that pneumatic skin flattening (PSF) significantly reduces pain and post-treatment erythema during high-energy IPL and laser hair removal while enhancing treatment efficacy.
October 2024 in “Journal of the Endocrine Society” This case report describes a patient with an ovarian steroid cell tumor that initially presented as non-classical adrenal hyperplasia, emphasizing the difficulty in differential diagnosis with hyperandrogenism and the importance of close clinical monitoring.
1 citations
,
July 2016 in “Livestock science” This study suggests that nerve growth factor may support hair follicle growth in Liaoning cashmere goats through pathways involving its receptor, TrkA, particularly during the anagen phase.
4 citations
,
February 2011 in “Annals of internal medicine” This article discusses polycystic ovary syndrome, outlining its prevalence, diagnostic criteria, and the progress made in understanding this underdiagnosed condition, but reports no new clinical findings.
2 citations
,
September 2022 in “Drug Delivery” This study found that a transdermal drug delivery system using nanostructured lipid carriers and polymeric microneedles for β-sitosterol significantly enhanced hair growth in testosterone-induced alopecia rats, suggesting potential for treating androgenic alopecia.
August 2008 in “Obstetrics & gynecology science” This review discusses the various features, diagnostic challenges, and associated immediate and long-term morbidities of polycystic ovary syndrome, highlighting its significant impact on quality of life and costs, but reports no new clinical results.
November 2021 in “International journal of life science and pharma research” This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.