Management of Colorectal Cancer Using Nanocarrier-Based Drug Delivery for Herbal Bioactives: Current and Emerging Approaches

Colorectal cancer (CRC) treatment faces challenges due to the side effects of modern medicines, prompting interest in herbal medicines known for their safety and effectiveness. Herbal bioactives like curcumin and resveratrol show promise against CRC but suffer from low bioavailability and efficacy. Novel drug delivery systems, including liposomes and nanoparticles, are being explored to enhance the solubility, bioavailability, and therapeutic effects of these herbal compounds. This review discusses CRC's pathophysiology, molecular pathways, and current diagnostic and treatment methods, with a focus on innovative delivery systems for herbal bioactives.