Management of Colorectal Cancer Using Nanocarrier-Based Drug Delivery for Herbal Bioactives: Current and Emerging Approaches

The document reviews the use of nanocarrier-based drug delivery systems for managing colorectal cancer, focusing on enhancing the bioavailability and therapeutic efficacy of herbal bioactives like curcumin, glycyrrhizin, and resveratrol. Various studies highlight the effectiveness of these systems, such as curcumin-encapsulated polymeric micelles and chitosan-based pH-sensitive micelles, in both in vitro and in vivo models. The review also discusses the potential of combining these bioactives with conventional chemotherapy drugs using nanocarriers to improve treatment outcomes and reduce side effects, underscoring the promise of these emerging approaches in colorectal cancer therapy.