Cutaneous Manifestations and Hormonal Changes Among Polycystic Ovary Syndrome Patients at a Tertiary Care Center

December 2021 in “ Cureus ”

Yara E Aljefri, Rana A Alahmadi, Rakan S Alajmi, Taif A Alkhamisi, Hadeel A Maaddawi, Ali Alraddadi, Awadh Alamri

hirsutism acne vulgaris androgenic alopecia luteinizing hormone follicle-stimulating hormone LH/FSH ratio obesity dyslipidemia acne hair loss LH FSH

TLDR Most women with Polycystic Ovary Syndrome (PCOS) have skin issues like excessive hair, acne, or hair loss. Hormone imbalances are common, and age, certain hormones, and hormone ratios can predict acne. Obesity, infertility, and high cholesterol are also common in these women.

The study involved 447 female patients with Polycystic Ovary Syndrome (PCOS), finding that 68% had at least one skin manifestation, most commonly hirsutism (47.3%), acne vulgaris (40.6%), and androgenic alopecia (20.3%). Hormonal abnormalities were common, with 49.1% having raised luteinizing hormone (LH) levels and 35.5% having a raised LH/follicle-stimulating hormone (FSH) ratio. Age, FSH, and LH/FSH ratio were significant predictors for acne vulgaris. The most common comorbidities were obesity (44.20%), infertility (25.70%), and dyslipidemia (17%). The study concluded that skin manifestations are prevalent in PCOS patients and play a significant role in diagnosis. However, no significant associations were found between androgenic alopecia and measured fasting blood glucose, HbA1c, or other hormones.

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16 / 16 results

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5 citations , September 2021 in “Dermatology Reports”

Skin problems like acne and excess hair in PCOS are common and linked to being overweight.

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1 citations , March 2020 in “International journal of reproduction, contraception, obstetrics and gynecology”

The study concluded that the most common skin problems in women with PCOS are excess hair, acne, oily skin, hair loss, dark skin patches, and skin tags.

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195 citations , March 2020 in “Clinica Chimica Acta”

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

research Skin Disease Related to Metabolic Syndrome in Women

11 citations , September 2019 in “International journal of women’s dermatology”

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

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49 citations , July 2019 in “The Journal of Clinical Endocrinology and Metabolism”

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

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317 citations , September 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

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60 citations , May 2018 in “Indian Journal of Psychological Medicine”

Women with PCOS often experience anxiety, depression, and a lower quality of life.

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7 citations , February 2018 in “International Journal of Dermatology”

AGA risk factors include age, smoking, hypertension for men, and age, dyslipidemia for women; lifestyle changes may help prevention.

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86 citations , October 2017 in “Translational pediatrics”

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

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28 citations , January 2017 in “Indian Dermatology Online Journal”

Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.

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53 citations , April 2016 in “JAMA Dermatology”

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

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Skin changes in women with PCOS are mainly due to hormonal imbalances.

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Korean patients with PCOS often have skin problems like acne and excess hair, with different symptoms based on their specific PCOS type.

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Many women with PCOS have undiagnosed health issues and show different symptoms based on the clinic they visit.

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26 citations , February 2011 in “Anais Brasileiros De Dermatologia”

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

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67 citations , February 2010 in “Acta Obstetricia et Gynecologica Scandinavica”

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

7 / 7 results

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17 citations , September 2017 in “Journal of Cosmetic Dermatology”

Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.

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28 citations , January 2017 in “Indian Dermatology Online Journal”

Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.

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July 2015 in “NEJM Journal Watch”

Diagnosing and treating PCOS in young people is difficult.

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60 citations , November 2014 in “Journal of the American Academy of Dermatology”

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

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10 citations , November 2010 in “Skin therapy letter”

Women with PCOS often have acne because of high androgen levels, and the article reviewed how to treat this type of acne.

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76 citations , January 2007 in “American Journal of Clinical Dermatology”

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

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67 citations , July 2006 in “Clinics in Dermatology”

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.