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The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Different types of skin cells play specific roles in development, healing, and cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

Histone modification is key in treating chronic inflammatory skin diseases.

EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

Stem cell therapy shows promise in improving burn wound healing.

Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.

Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

STAT5 activation is crucial for starting the hair growth phase.

Notch signaling disruptions can cause various skin diseases.

Immune cells called Treg cells are essential for hair growth and regeneration.

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.