June 2017 in “Journal of The American Academy of Dermatology” Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.
32 citations
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April 2016 in “Aaps Pharmscitech” This study found that nanostructured lipid carriers enhanced the skin penetration and retention of minoxidil compared to solid lipid nanoparticles, suggesting they could be a promising method for topical delivery.
5 citations
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November 2007 in “British journal of nursing” This article discusses the importance of nurses' understanding of topical emollient therapy for patients with eczema, but it does not provide new clinical results.
22 citations
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January 2012 in “Mediators of inflammation” This review discusses the potential benefits of nonantibiotic macrolides for treating inflammatory skin disorders and reports no new clinical results.
January 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that the optimized nanostructured lipid carrier formulation effectively enabled caffeine to penetrate and accumulate in hair follicles, suggesting potential for intrafollicular delivery in treatments for hair loss.
5 citations
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December 2011 in “Drug Research” This study found that cortexolone 17α-propionate showed strong topical antiandrogenic activity, outperforming progesterone and several known antiandrogens, but lacked systemic antiandrogenic effects in animal models.
May 2026 in “Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology” The researchers reported that zinc carbonate nanoparticles stabilized with polyvinylpyrrolidone did not show local irritant or skin-resorptive effects in preclinical tests on rabbits and rats.
159 citations
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July 2014 in “Molecular pharmaceutics” This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.
28 citations
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January 2005 in “PubMed” This review discusses the use, mechanism, and side effects of topical immunomodulators in treating immune-mediated skin disorders and reports no new clinical results, urging further research on experimental agents.
December 2024 in “PubMed” This study evaluates the compatibility of six active pharmaceutical ingredients, including finasteride and spironolactone, with TrichoFoam™, a foam vehicle used in personalized treatments for alopecia, though it does not report specific results.
August 2025 in “International Journal of Pharmaceutical Sciences and Nanotechnology” This study formulated a minoxidil nanoemulgel with improved solubilization and skin penetration, demonstrating a high entrapment efficiency and sustained drug release in vitro, which suggests potential improvements in treating androgenetic alopecia compared to conventional formulations.
3 citations
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September 1989 in “Journal of Investigative Dermatology” This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.
1 citations
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August 2017 in “Asian Journal of Pharmaceutical and Clinical Research” The 1% ethyl acetate fraction ethosomal gel from Nothopanax scutellarium leaves promotes hair growth but can mildly irritate the skin.
9 citations
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February 2011 in “Biologics: Targets & Therapy” This review discusses topical calcineurin inhibitors for cutaneous lupus erythematosus and reports no new clinical findings; the authors emphasize the need for more comparative studies with corticosteroids.
42 citations
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July 2014 in “European journal of pharmaceutics and biopharmaceutics” This study established a stable formulation for caffeine nanocrystals in specific solvent mixtures, which could be used to test their potential for enhanced hair follicle targeting and penetration.
This study found that nanoparticles developed with minoxidil-loaded thiolated β-cyclodextrins showed improved drug retention on hair surfaces and did not cause skin irritation in rabbits, suggesting potential for topical scalp disease treatment.
1 citations
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April 2009 in “Expert Review of Dermatology” This study found that the once-daily gel combining calcipotriene and betamethasone dipropionate was more effective and faster in treating scalp psoriasis compared to individual treatments, with a similar safety profile.
January 2019 in “Egyptian Journal of Dermatology and Venereology /Egyptian Journal of Dermatology and Venerology” This study investigated the efficacy and safety of a gel combining topical calcipotriol and steroid for alopecia areata. It found the combination worked similarly to steroids alone in reducing hair loss, but with fewer side effects.
June 2019 in “International journal of dermatology and venereology” This case report highlights a 73-year-old man developing rosacea-like dermatitis after taking icotinib hydrochloride for NSCLC, suggesting awareness of this side effect is important for clinicians.
3 citations
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July 2019 in “Supportive Care in Cancer” The lotion CG428 did not show effectiveness in treating permanent hair loss in breast cancer survivors.
61 citations
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June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that liposomes coated with cationic polymers, chitosan and Eudragit EPO, showed improved physicochemical stability and enhanced skin diffusion of aciclovir and minoxidil compared to uncoated liposomes.
17 citations
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January 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” Isoconazole nitrate stays effective in skin and hair follicles for up to two weeks after use.
4 citations
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February 2018 in “Jurnal teknologi” This study found that Kaempferia galanga ethanolic extract has potential as an antifungal agent in an oil-in-water cream formulation, exhibiting stable physicochemical properties in laboratory tests.
February 2025 in “Indian Dermatology Online Journal” The study found that both mometasone and calcipotriol ointments effectively reduced alopecia severity in localized alopecia areata, with calcipotriol having fewer side effects, while tacrolimus showed no significant effect.
This summary highlights in vitro and in vivo experiments showing that nano-sized liposomes with bound polihexanide penetrate hair follicles more effectively and may extend antiseptic effects longer than conventional polihexanide solutions.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a herbal hair cream containing natural ingredients like Jamalgota and Amla was developed and evaluated, with Batch 3 showing promising results in texture, pH balance, spreadability, and stability, suggesting it may be a safe and effective option for managing alopecia.
1 citations
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January 2013 in “Annals of Dermatology” This case report describes an 11-year-old girl with eosinophilic pustular folliculitis that showed significant improvement with naproxen after being unresponsive to other treatments.
7 citations
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September 2013 in “Current Dermatology Reports” This review summarizes existing literature on the safety of commonly used dermatologic medications during pregnancy but does not present new clinical findings, aiming to assist physicians with prescribing decisions.
April 2023 in “Dermatology practical & conceptual” This study observed that a tacrolimus solution (0.1%) applied to the scalp was effective and well-tolerated for treating inflammatory scalp conditions, with 72.7% of patients showing an excellent response after 2 months of treatment, which persisted after 6 months.
March 2018 in “Vìsnik farmacìï” This study identified flavonoids and phytosterols in a medicated cosmetic cream developed for androgenic alopecia and proposed methods for their identification and quantification.