TLDR Mixing calcipotriol with a steroid is almost as effective as using a steroid alone for alopecia areata and has fewer side effects.
The study conducted in 2019 involved 40 patients with mild-to-moderate untreated Alopecia Areata (AA), divided into two groups of 20. Group A was treated with a topical steroid (betamethasone valerate 0.1%) twice daily for 12 weeks, while Group B was treated with a gel containing calcipotriol 0.005% mixed with betamethasone dipropionate 0.05% twice daily for the same period. The Severity of Alopecia Tool (SALT) score was used to evaluate the treatment outcomes. Both treatments resulted in a significant decrease in SALT scores after 3 months, with no significant differences between the two groups, suggesting similar efficacy. However, the group treated with the gel containing calcipotriol and topical steroid reported minimal adverse effects, making it a promising therapeutic option for AA.
Cited in this study
4 / 4 results
44 citations
,
December 2016 in “Journal of The American Academy of Dermatology” The updated SALT II tool offers a more precise way to measure scalp hair loss.
71 citations
,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” There are no FDA-approved treatments for Alopecia Areata, and current options have varying success and relapse rates.
51 citations
,
January 2012 in “Annals of dermatology/Annals of Dermatology” A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
146 citations
,
July 2003 in “Journal of the American Academy of Dermatology” Clobetasol propionate ointment can help some people with total hair loss regrow hair.
1 citations
,
December 2022 in “Journal of cosmetic dermatology” The combination of vitamin D analogues with potent steroids is a favorable treatment for alopecia areata with fewer side effects.
January 2019 in “Egyptian Journal of Dermatology and Venereology /Egyptian Journal of Dermatology and Venerology” Mixing calcipotriol with a steroid is almost as effective as using a steroid alone for alopecia areata and has fewer side effects.