Comparative Evaluation of the Efficacy of Topical Tacrolimus 0.03% and Topical Calcipotriol 0.005% Mixed With Betamethasone Dipropionate Versus Topical Clobetasol 0.05% in Treatment of Alopecia Areata: A Clinical and Trichoscopic Study

    December 2022 in “ Journal of cosmetic dermatology ”
    Amany Nassar, Mona Elradi, Mona Radwan, Waleed Albalat
    Studysummary This study found that combining a potent steroid with a vitamin D analogue may offer more convenient treatment for localized alopecia areata than using a superpotent steroid alone, with comparable efficacy but fewer side effects.
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    Research cited in this study 12

    1. Efficacy of Topical Clobetasol Propionate 0.05% Ointment and Topical Tacrolimus 0.1% Ointment in Treatment of Alopecia Areata: Randomized Controlled Trial Pakistan Journal of Medical and Health Sciences · 2022
    2. Comparative Evaluation of Efficacy Between Topical Calcipotriol Used Along With Topical Clobetasol and Topical Clobetasol Monotherapy in Treatment of Alopecia Areata: A Randomized Clinical Trial Journal of clinical and diagnostic research · 2021
    3. Consensus on the Treatment of Alopecia Areata – Brazilian Society of Dermatology Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia · 2020
    4. Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study Dermatology and therapy · 2020
    5. Italian Guidelines in Diagnosis and Treatment of Alopecia Areata Giornale italiano di dermatologia e venereologia · 2019
    6. Alopecia Areata Predictive Score: A New Trichoscopy-Based Tool to Predict Treatment Outcome in Patients with Patchy Alopecia Areata Journal of Cosmetic Dermatology · 2019
    7. Topical Calcipotriol vs Narrowband Ultraviolet B in Treatment of Alopecia Areata: A Randomized-Controlled Trial Archives of Dermatological Research · 2019
    8. Alopecia Areata and Alopecia Areata Incognita Elsevier eBooks · 2018
    9. Efficacy and Safety of Topical Calcipotriol in Management of Alopecia Areata: A Pilot Study Dermatologic Therapy · 2017
    10. Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study PubMed · 2015
    11. British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012 British Journal of Dermatology · 2012
    12. Diphencyprone and Topical Tacrolimus as Two Topical Immunotherapeutic Modalities: Are They Effective in the Treatment of Alopecia Areata Among Egyptian Patients? A Study Using CD4, CD8, and MHC II as Markers Journal of dermatological treatment · 2010