Efficacy of Topical Clobetasol Propionate 0.05% Ointment and Topical Tacrolimus 0.1% Ointment in Treatment of Alopecia Areata: Randomized Controlled Trial

    June 2022 in “ Pakistan Journal of Medical and Health Sciences ”
    Farman Ullah, Muhammad Dawood, Nasma Noor, Sadia Hameed
    Image of study
    TLDR Topical clobetasol propionate 0.05% ointment is more effective in promoting hair regrowth in patients with alopecia areata than topical tacrolimus 0.1% ointment.
    The randomized control trial involved 116 patients with alopecia areata of the scalp, divided into two groups. Group A was treated with topical clobetasol propionate 0.05% ointment, and Group B with topical tacrolimus 0.1% ointment, both applied twice daily for 3 months. The study found that 79.31% of patients in Group A showed effective hair regrowth, compared to 44.82% in Group B, with a significant P-value of 0.00013. Therefore, the study concluded that topical clobetasol propionate 0.05% ointment was more effective in promoting hair regrowth in patients with alopecia areata.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 61 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Just find a cure already, I am totally done

      in Chat  161 upvotes 7 months ago
      The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.

      community This and ketoconazole 2% life changing

      in Ketoconazole  69 upvotes 1 year ago
      The post discusses the user's experience with hair loss treatment using finasteride, clobetasol propionate, and ketoconazole shampoo. The conversation warns about the potential side effects of clobetasol, a powerful topical steroid, and emphasizes its short-term usage.

      community Hair Loss Inflammation Prevention Stack

      in Research/Science  42 upvotes 4 days ago
      The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  413 upvotes 1 week ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

    Related Research

    5 / 5 results