Eosinophilic Pustular Folliculitis Involving Labial Mucosa, Which Improved with Naproxen

An 11-year-old girl with eosinophilic pustular folliculitis (EPF) involving the labial mucosa showed significant improvement with naproxen after other treatments, including systemic prednisolone and topical corticosteroids, were ineffective. EPF, characterized by eosinophilic infiltration of hair follicles, has various treatment options, but NSAIDs like naproxen may be particularly effective, as demonstrated in this case. This suggests naproxen could be a viable first-line treatment for EPF in children, despite the condition's complex etiology and pathogenesis.