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GlossaryNonsteroidal Anti-Inflammatory Drugs (NSAIDs)

reduce inflammation, pain, and fever without using steroids

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) are a class of medications that reduce inflammation, relieve pain, and lower fever. Unlike steroids, they do not contain corticosteroids. Common examples include ibuprofen and aspirin. They work by inhibiting enzymes called COX-1 and COX-2, which are involved in the production of prostaglandins, compounds that promote inflammation, pain, and fever.

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research Effect of Non-Steroidal Anti-Inflammatory Drugs on Post-Surgical Complications Against the Backdrop of the Opioid Crisis

36 citations, January 2018 in “Burns & Trauma”

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

research Cutaneous Drug Reactions

1 citations, January 2010 in “Elsevier eBooks”

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

research Associations Between Variants in the Cyclooxygenase 2 Enzyme Gene (PTGS2) and Development of Benign Prostate Enlargement

November 2012 in “The Journal of Urology”

Certain gene variants may raise the risk of prostate enlargement, but taking NSAIDs could reduce this risk.

research Pharmacologic Management of Acute Attacks of Migraine and Prevention of Migraine Headache

201 citations, November 2002 in “Annals of internal medicine”

Use NSAIDs for immediate migraine relief and β-blockers for prevention; tailor treatment to the individual.

research Factors to Consider When Selecting Antiulcer Drugs for a Formulary

August 1994 in “Drugs & Therapy Perspectives”

The document concludes that H2-antagonists and proton pump inhibitors are highly effective for ulcers, eradicating Helicobacter pylori is important to prevent recurrence, and misoprostol helps with NSAID-related ulcers.

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community Painkillers May Block Minoxidil

in Research/Science 12 upvotes 2 weeks ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 7 months ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community "Minoxidil and Caffeine: Reason behind hyper responders and non-responders."

in Research/Science 31 upvotes 1 year ago

Minoxidil and caffeine may interact, affecting hair growth results. Users shared mixed experiences, with some noticing improvements without caffeine and others still seeing results despite coffee consumption.

community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

in Research/Science 3 upvotes 1 month ago

DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

community Bryan johnson mail about his routine

in Chat 64 upvotes 7 months ago

A user shared their successful hair loss and gray hair reversal routine, which includes Minoxidil, Cetirizine HCl, Latanoprost, Dutasteride, Melatonin, Caffeine, Tretinoin, Vitamin D3, and Vitamin E. They also use a red light cap, oral Minoxidil, and are developing new treatments.

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