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    Glossary Neurogenic Inflammation

    inflammation triggered by nerve-released chemicals causing redness and pain

    Neurogenic inflammation is a type of inflammation triggered by the nervous system. It occurs when nerve fibers release certain chemicals, like substance P and calcitonin gene-related peptide (CGRP), which cause blood vessels to expand and immune cells to become activated, leading to redness, swelling, and pain. This process is often involved in conditions like migraines, asthma, and some skin disorders.

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    Research 30 of 815

    1. Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor American Journal of Pathology · 2004 · 108 citations
    2. Role of neurogenic inflammation in the pathogenesis of alopecia areata The Journal of Dermatology · 2024 · 8 citations
    3. Neurogenic skin inflammation in stress‐triggered inhibition of hair growth in mice is promoted via nerve growth factor‐dependent pathways Experimental Dermatology · 2004
    4. Frontal Fibrosing Alopecia and Increased Scalp Sweating: Is Neurogenic Inflammation the Common Link Skin Appendage Disorders · 2015 · 15 citations
    5. LB1059 Neuromediators associated with neurogenic skin inflammation promote M2 differentiation of macrophages in human skin ex vivo Journal of Investigative Dermatology · 2024
    6. Neuroimmunology of Stress: Skin Takes Center Stage Journal of Investigative Dermatology · 2006 · 375 citations
    7. Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control Experimental Dermatology · 2005 · 127 citations
    8. Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin Brain Behavior and Immunity · 2004 · 115 citations
    9. Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role? Journal of Investigative Dermatology · 2009 · 69 citations
    10. Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways Journal of Molecular Medicine · 2007 · 66 citations
    11. Sensitive skin Expert Review of Dermatology · 2013 · 29 citations
    12. Neuropeptídeos na pele Anais Brasileiros de Dermatologia · 2003 · 27 citations
    13. Indications for Peripheral and Central Sensitization in Patients With Chronic Scalp Pain (Trichodynia) The Clinical Journal of Pain · 2012 · 16 citations
    14. Substance P in keratosis follicularis spinulosa decalvans JAAD case reports · 2015 · 4 citations
    15. Cuero cabelludo sensible: diagnóstico y manejo práctico 2022 · 2 citations
    16. Effectiveness of Botulinum Toxin Type A for Trichodynia Associated with Hair Loss Disorders: A Retrospective Study Dermatology and Therapy · 2026
    17. Use of Botulinum Toxin in Dermatology Journal of applied cosmetology · 2024
    18. Topical Application of Aprepitant Inhibits Erlotinib-induced Facial Dermatitis/Hair Loss Journal of dermatology and skin science · 2024
    19. ALOPESIA AREATA SEBAGAI SEKUELE POST REINFEKSI COVID-19 Media Dermato Venereologica Indonesiana · 2023
    20. Effects of botulinum toxin type A on histamine-induced itch and vasomotor responses in human skin Toxicon · 2008
    21. Remission of hair loss and induction of hair regrowth by botulinum neurotoxin A in mice Toxicon · 2008
    22. ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators Experimental dermatology · 2006
    23. <i>In vitro</i> interactions between sensory nerves, epidermis, hair follicles and capillaries in a tissue‐engineered reconstructed skin Experimental Dermatology · 2004
    24. 1372 Biological effects of electrical epilation on human hair follicles and perifollicular skin ex vivo 2018
    25. Neuroimmunoendocrine circuitry of the ‘brain-skin connection’ Trends in Immunology · 2005 · 293 citations
    26. Is there a ‘gut–brain–skin axis’? Experimental Dermatology · 2010 · 185 citations
    27. Hyaluronic Acid Profhilo® Alleviates Skin Inflammation and Spinal Neuroimmune Alterations in a Mouse Model of Atopic Dermatitis Medicina · 2026
    28. Segmental Vitiligo Springer eBooks · 2019 · 2 citations
    29. The clinical features, muscle pathology, and role of autophagy in anti-Ku-positive patients Frontiers in Immunology · 2025
    30. Immune Privilege Collapse and Alopecia Development: Is Stress a Factor Skin Appendage Disorders · 2017 · 51 citations