Indications for Peripheral and Central Sensitization in Patients With Chronic Scalp Pain (Trichodynia)

    December 2012 in “ The Clinical Journal of Pain ”
    Ruth Defrin, Raziel Lurie
    Studysummary This study found that trichodynia is associated with both peripheral and central sensitization, potentially linked to hair cycle abnormalities and chronic pain through proinflammatory agents.
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    Research cited in this study 8

    1. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005
    2. The Presence of Trichodynia in Patients With Telogen Effluvium and Androgenetic Alopecia International Journal of Dermatology · 2003
    3. Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003
    4. Assessment of Hair Loss: Clinical Relevance of Hair Growth Evaluation Methods Clinical and Experimental Dermatology · 2002
    5. Hair Pain (Trichodynia): Frequency and Relationship to Hair Loss and Patient Gender Dermatology · 2002
    6. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    7. Chronic Telogen Effluvium: Incidence, Clinical and Biochemical Features, and Treatment Archives of Dermatology · 1999
    8. Scalp Dysesthesia: A Study on Chronic Pain and Itchiness Archives of Dermatology · 1998

    Related research 1

    1. Indications for Peripheral and Central Sensitization in Patients With Chronic Scalp Pain (Trichodynia) The Clinical Journal of Pain · 2012