Trichodynia: A Review of the Literature

Trichodynia, a condition characterized by a painful sensation on the scalp associated with hair loss, affects about 20% of patients with hair loss and is more commonly reported by women. The intensity of the pain can vary, with a "burning" sensation being the most severe. The review from 2015 suggests that the condition may be linked to the release of substance P and inflammation around hair follicles, as seen in alopecia areata and other inflammatory scalp conditions. Trichodynia is often accompanied by anxiety and may not become apparent until after hair shedding begins. Treatment options are not well-established but could include anti-inflammatory medications, antidepressants, or substance P inhibitors. The review highlights that trichodynia is an underrecognized symptom in hair loss patients, especially those with telogen effluvium, and suggests inflammation as a potential underlying cause.