Use of Botulinum Toxin in Dermatology

The review "Use of Botulinum Toxin in Dermatology" by Marcelina Kądziela discusses the potential of Botulinum toxin (BoNT) in treating various dermatological conditions. The study suggests that BoNT is effective in treating Hidradenitis Suppurativa (HS) by reducing inflammation and pain, although controlled trials are needed for conclusive evidence. In rosacea, BoNT injections can reduce erythema, but the mechanism is not fully understood. For androgenetic alopecia, BoNT injections have been shown to increase hair density, possibly through modulation of the dermal papilla and relaxation of scalp muscles. BoNT also shows promise in treating plaque psoriasis, likely by reducing neurogenic inflammation. In primary hyperhidrosis, BoNT significantly reduces sweat production and severity, making it a viable second-line treatment. Despite its potential, BoNT use requires caution due to associated risks, and rigorous clinical trials are needed to definitively establish safety and efficacy. The review emphasizes the need for continued research to refine BoNT therapy and expand its dermatological applications.