Botulinum Toxin Type A for the Management of Hidradenitis Suppurativa

January 2021 in “ PubMed ”

Huanhuan Qu, Linbo Gao

hidradenitis suppurativa hair follicles botulinum toxin type A antibiotics surgery HS Botox

TLDR Botulinum toxin type A injections may help treat hidradenitis suppurativa.

The document reviewed the chronic skin disease hidradenitis suppurativa (HS), which is linked to hair follicles and characterized by painful lesions. It discussed the complex etiology involving genetic, inflammatory, microbial, and lifestyle factors. Traditional treatments, including antibiotics and surgery, have variable efficacy. The article highlighted recent findings that botulinum toxin type A injections showed promise in managing HS, offering a potential new treatment avenue.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Research cited in this study

4 / 4 results

Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages

research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages

25 citations , December 2018 in “Human Molecular Genetics”

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

research The Follicular Skin Microbiome in Patients With Hidradenitis Suppurativa and Healthy Controls

220 citations , May 2017 in “JAMA dermatology”

Patients with hidradenitis suppurativa have a different skin microbiome compared to healthy people.

research Clinical and Histopathological Characteristics in Patients with Scarring Folliculitis Type of Acne Inversa

10 citations , January 2017 in “Dermato-Endocrinology”

Scarring folliculitis type of acne inversa is linked to specific symptoms and lifestyle factors like smoking and being overweight.

research Hormonal Therapies for Hidradenitis Suppurativa: A Review

24 citations , January 2017 in “Dermatology online journal”

Hormonal therapies might help treat hidradenitis suppurativa, but treatment is complex and personalized.

Similar Research

5 / 813 results

research Off-Label Use of Botulinum Toxin in Dermatology: Current State of the Art

5 citations , May 2022 in “Molecules”

Botulinum toxin is effective for various skin conditions, but more research and awareness of side effects are needed.

research Follicular and Scarring Disorders in Skin of Color: Presentation and Management

30 citations , May 2014 in “American Journal of Clinical Dermatology”

The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.

research Hidradenitis Suppurativa: A Practical Review of Possible Medical Treatments Based on Over 350 Hidradenitis Patients

90 citations , April 2013 in “Dermatology online journal”

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

research Acne-Associated Syndromes

January 2019 in “Springer eBooks”

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts

7 citations , July 2019 in “International archives of internal medicine”

Common skin conditions can greatly affect a person's mental health and social life.