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This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.

This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.

This study found that extracellular vesicles from stimulated human dermal fibroblasts enhanced hair follicle growth ex vivo by activating dermal papilla cells and involving the Norrin and β-catenin pathways.

This article discusses a novel device for applying mediums to human and animal tissues and reports no new clinical results, focusing on its potential for precise applications and enhanced cell transplants.

In this study, researchers showed that multiphoton microscopy with fluorescent protein tagging enables single-cell imaging and tracking in live transgenic mice, offering new insights into cell dynamics in stem cell research compared to traditional histological methods.

Flubendazole in a nanoemulsion can potentially treat lung cancer and cryptococcal meningitis effectively and safely.

This study introduced ElixirSeeker2, a computational framework for designing anti-aging peptides, and found that some newly identified peptides significantly delayed cellular senescence and enhanced cellular and locomotor functions in aged Caenorhabditis elegans.

This report introduces a tissue-engineered nerve conduit combining hfNCSCs-derived neurons and acellular nerve grafts to potentially repair long-distance peripheral nerve injuries.

This study found that a nanofiber wound dressing made of CQD/Si NP/SF significantly inhibits bacterial growth and accelerates skin wound healing and hair follicle regeneration in animal models.

This study highlights that solid lipid nanoparticles may improve the absorption and bioavailability of poorly soluble drugs, offering advantages over conventional formulations for various administration routes.

This study found that nano-transferosomal gel formulations of finasteride improved its delivery across skin layers, potentially reducing major side effects associated with oral administration for treating male pattern baldness.

This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.

This study found that nanostructured lipid carriers could serve as a promising vehicle for topical Acitretin delivery in psoriasis treatment, potentially reducing oral side effects and enhancing patient compliance.

In this study, researchers developed a novel temperature-sensitive biopolymer-based drug delivery system that enhanced the transdermal delivery of ISX9, a neurogenesis inducer, resulting in more effective hair follicle regrowth and signal pathway activation in vivo compared to traditional topical application.

This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.

In this study, researchers used a 3D in vitro organ culture system to show that rifampicin-loaded lipid nanocapsules can penetrate hair follicles more effectively than free rifampicin, highlighting the potential advantage of nanocarrier-based antibiotic treatments for follicular infections.

This study demonstrated that genetically engineered, ATP-responsive nanozymes effectively reduce cardiac fibrosis by targeting activated cardiac fibroblasts, resulting in decreased myofibroblast accumulation and improved cardiac function, suggesting that this approach has significant potential for therapeutic applications.

This study found that engineered extracellular vesicles (293F-EGF-EV), enriched in EGF mRNA, significantly aided skin wound healing in vitro and in a rat model by promoting fibroblast activity and improving wound recovery through processes like angiogenesis and reduced scarring.

This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.

This study reports that triboelectro-responsive DNA hydrogels, enhanced with conductive polymers and triboelectric stimulation, effectively accelerate wound healing and exhibit strong anti-bacterial and anti-inflammatory properties, achieving 99.8% closure of bacterium-infected diabetic wounds in 14 days.

This study found that sub-100 nm solid lipid nanoparticles showed the most effective skin penetration and depth, primarily via hair follicles, in rat skin evaluations.

This study found that a curcumin-labeled particle-associated antiseptic penetrated deeper into hair follicles in porcine skin than particles without antiseptic.

In this mouse study, researchers found that nanoparticles loaded with umbilical cord-derived stem cell membranes and minoxidil enhanced hair growth by improving drug solubility and transdermal delivery, increasing VEGF, IGF-1, MKI67, and CTNNB protein levels in skin tissue compared to regular minoxidil.

This study found that Coenzyme Q10 delivered through transethosomes improved clinical outcomes for androgenic alopecia patients compared to CoQ10 solution.

This review discusses the progress and challenges in delivering CRISPR/Cas9 systems for in vivo genome editing, highlighting current methods and opportunities for future therapeutic applications.

This study found that extracellular vesicles derived from hyaluronic acid-stimulated induced pluripotent stem cells significantly improved hair growth in a model of androgenetic alopecia in mice by enhancing Wnt/β-catenin signaling and regulating androgen receptor activity, showing comparable results to the commonly used treatment finasteride.

This study observed that dissolving microneedles made from PVP-K90 and HPMC E50, incorporating Oryza sativa L. extract complex, showed enhanced transfollicular skin penetration and maintained safety for keratinocytes, with the P25H5 formulation demonstrating faster dissolution and greater effectiveness.