TLDR Solid lipid nanoparticles can improve how well drugs that don't dissolve in water work and are safe.
Six years ago, a study from MM College of Pharmacy and MM University in India explored the potential of Solid Lipid Nanoparticles (SLN) as a drug delivery system for poorly water-soluble drugs. The researchers found that SLN could enhance the solubility, stability, permeability, and bioavailability of these drugs, with minimal side effects. This technology was particularly beneficial for oral administration, overcoming enzymatic barriers in the gastrointestinal tract that often hinder the effectiveness of such drugs. The study also highlighted the potential applications of SLN in treating various diseases, including tuberculosis, cancer, diabetes, and several nervous system-related disorders.
12 citations
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January 2018 in “Journal of Drug Delivery Science and Technology” The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
26 citations
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December 2022 in “Molecules” Nanotechnology can improve treatments for skin discoloration.
559 citations
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October 2020 in “Frontiers in Molecular Biosciences” Solid lipid nanoparticles are promising for safe and effective drug delivery but need more research for clinical use.
47 citations
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September 2015 in “Journal of Drug Delivery Science and Technology” Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
February 2024 in “International Journal For Multidisciplinary Research” Nanostructured lipid carriers are effective for treating hyperpigmentation in women aged 30-40.
December 2013 in “Biomedical and biopharmaceutical research” Nanotechnology shows promise for better drug delivery and cancer treatment.
5 citations
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December 2023 in “Materials” Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
