A Novel 3D Printed Model of Infected Human Hair Follicles to Demonstrate Targeted Delivery of Nanoantibiotics
July 2024
in “
ACS Biomaterials Science & Engineering
”
3D printed model human hair follicles antibiotic nanocarriers follicular infections collagen matrix 3D printed scaffold fluorescent nanoparticles rifampicin-loaded lipid nanocapsules free rifampicin nanoencapsulated form bacterial reduction follicle microenvironment nanocarriers targeted therapy 3D model hair follicles antibiotic carriers infections collagen scaffold nanoparticles rifampicin capsules rifampicin encapsulated antibiotics bacteria reduction microenvironment carriers targeted treatment
Studysummary In this study, researchers used a 3D in vitro organ culture system to show that rifampicin-loaded lipid nanocapsules can penetrate hair follicles more effectively than free rifampicin, highlighting the potential advantage of nanocarrier-based antibiotic treatments for follicular infections.
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