Preparation, Physicochemical and Clinical Evaluation of Aminexil Niosome in Prevention of Androgenetic Alopecia
January 2019
Studysummary This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.
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The study concluded that niosomes, formed by combining Span/Tween/Cholesterol, provided a stable carrier for aminexil, enhancing its penetration through rat skin and showing greater clinical efficacy in preventing androgenetic alopecia compared to conventional aminexil solutions. Additionally, niosomal formulations offered the advantage of not requiring propylene glycol, a sensitizing co-solvent, making them a preferable option for topical hair growth treatments.
