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research Combinatorial Therapy of Letrozole- and Quercetin-Loaded Spanlastics for Enhanced Cytotoxicity against MCF-7 Breast Cancer Cells

39 citations , August 2022 in “Pharmaceutics”

This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.

research Formulation-by-Design of Efinaconazole Spanlastic Nanovesicles for Transungual Delivery Using Statistical Risk Management and Multivariate Analytical Techniques

25 citations , July 2022 in “Pharmaceutics”

This study optimized efinaconazole spanlastic nanovesicles using risk management and multivariate analysis for potential transungual delivery to treat onychomycosis, achieving improved drug permeability and dissolution efficiency.

research Spanlastic Nano-Vesicles: A Novel Approach to Improve the Dissolution, Bioavailability, and Pharmacokinetic Behavior of Famotidine

14 citations , November 2024 in “Pharmaceuticals”

This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.

research Development and Characterization of In Situ Gelling Nasal Cilostazol Spanlastics

8 citations , January 2025 in “Gels”

This study developed cilostazol-loaded formulations for nose-to-brain delivery, finding that these formulations improved cilostazol's bioavailability by enhancing solubility, absorption, and permeability, achieving nearly 100% drug release in vitro within 2 hours.

research Spangled hair in siblings

5 citations , January 2009 in “International Journal of Trichology”

This case report documents a rare association between atopic eczema and pili annulati in two siblings from north India, an unusual finding not previously reported in the literature.

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Community Join

5 / 238 results

community Spanish Ex footballer Joaquín takes Dutasteride

in Finasteride/Dutasteride 42 upvotes 10 months ago

Dutasteride and oral minoxidil are commonly used in Spain for hair loss, with a typical dose of 0.5 mg dutasteride and 2.5-5 mg oral minoxidil. Some users report side effects like erectile dysfunction when using finasteride and minoxidil.

community Spanish dermatologist suggests sulforaphane for AGA

in Research/Science 13 upvotes 2 years ago

A Spanish dermatologist suggests sulforaphane for androgenetic alopecia (AGA) due to its potential to remove DHT metabolites, though high dosages are needed. A topical formulation might be possible.

community A Spanish doctor shared Verteporfin video

7 upvotes 2 years ago

A Spanish doctor shared a video about Verteporfin for hair loss. The conversation mentions Minoxidil, finasteride, and RU58841 as treatments.

community Progress pictures in the span of 3 months

49 upvotes 11 months ago

The user shared progress pictures showing hair improvement over three months using a treatment of 5% minoxidil and 0.1% finasteride solution, along with occasional biotin and multivitamins. Another user discussed their regimen of topical minoxidil, oral minoxidil, finasteride, iron supplements, and dutasteride, seeking advice on application routines.

community Dermatologist explains the treatment used on a NW4 patient (video in Spanish)

in Treatment 43 upvotes 1 year ago

A 29-year-old male with androgenic alopecia was treated with oral Dutasteride, oral Minoxidil, and injectable Dutasteride, showing progress in 9 months. Some users believe Dutasteride mesotherapy is unnecessary and question its effectiveness compared to topical applications.

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Clinics

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Experts

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