Development and Characterization of In Situ Gelling Nasal Cilostazol Spanlastics

    January 2025 in “ Gels ”
    Maryana Salamah, Mária Budai-Szűcs, Bence Sipos … Ildikó Csóka
    Studysummary This study developed cilostazol-loaded formulations for nose-to-brain delivery, finding that these formulations improved cilostazol's bioavailability by enhancing solubility, absorption, and permeability, achieving nearly 100% drug release in vitro within 2 hours.
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    Research cited in this study 3

    1. Spanlastic-Laden Nanogel for Dermal Delivery of Bimatoprost in Androgenic Alopecia International journal of pharmaceutics. X · 2024
    2. Formulation of Chitosan-Coated Brigatinib Nanospanlastics: Optimization, Characterization, Stability Assessment and In-Vitro Cytotoxicity Activity Against H-1975 Cell Lines Pharmaceuticals · 2022
    3. Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia Pharmaceutics · 2020