PVA-Based Nanofiber Containing CQDs Modified with Silica NPs and Silk Fibroin Accelerates Wound Healing in a Rat Model

The study investigated the effects of a PVA-based nanofiber containing carbon quantum dots (CQDs), silica nanoparticles (Si NPs), and silk fibroin (SF) on wound healing in a rat model. The nanocomposite demonstrated high antibacterial activity against S. aureus and E. coli, and was non-toxic, promoting cell viability and proliferation in NIH 3T3 fibroblast cells. The PVA–CQD/Si NP/SF nanofiber effectively accelerated skin and hair follicle regeneration, making it a promising wound dressing for inhibiting bacterial growth and promoting skin wound repair and hair regeneration.