PVA-Based Nanofiber Containing CQDs Modified with Silica NPs and Silk Fibroin Accelerates Wound Healing in a Rat Model

This study focused on developing a novel wound dressing using a PVA-based nanofiber containing carbon quantum dots (CQDs), silica nanoparticles (Si NPs), and silk fibroin (SF), which was tested in a rat model. The research demonstrated that the PVA-CQD/Si NP/SF nanofiber effectively accelerated skin and hair follicle regeneration, making it a promising candidate for wound healing applications. The nanocomposite exhibited high antibacterial activity against S. aureus and E. coli, and it was non-toxic, promoting cell viability and proliferation. The study concluded that this nanofiber could inhibit bacterial growth and enhance skin wound repair and hair regeneration.