The Hair Loss Encyclopedia

Gold Nanoparticle/Silk Fibroin-Based Nanofiber Enhances Skin Regeneration

June 2025 in “ Journal of Pharmacy and Pharmacology ”

Ozan Özcan, Elif Tufan, Aleyna Muhan, Esın Ak, Göksel Şener, Tuğba Tunalı Akbay

gold nanoparticles silk fibroin nanofiber wound healing hair follicle formation re-epithelialization

TLDR Gold nanoparticles with silk fibroin improve wound healing better than silk fibroin alone.

The study investigated the wound-healing potential of gold nanoparticles combined with silk fibroin-based nanofiber using a green chemistry approach. Conducted on 40 rats divided into two treatment periods (7 and 21 days), the research compared control, silver, silk fibroin, and silk + gold nanoparticle groups. Results showed that the gold nanoparticle/silk fibroin-based nanofiber effectively restored skin damage indicators to normal levels and promoted hair follicle formation and re-epithelialization at the wound site. The study concluded that the addition of gold nanoparticles to silk fibroin significantly enhanced wound-healing properties compared to silk fibroin alone.

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Research cited in this study

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Wound Healing: A Cellular Perspective

research Wound Healing: A Cellular Perspective

1160 citations , November 2018 in “Physiological Reviews”

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

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6 / 249 results

community Seeking advice about whether expensive hair treatment is worth it

in Treatment 1 upvotes 5 months ago

The conversation is about hair loss treatments, with users recommending Finasteride and Minoxidil as the gold standard. They suggest microneedling and laser therapy as cost-effective home treatments, while expressing skepticism about the expensive clinic treatment and V2X product.

community Any Indian Min/Fin users? Your experience with Indian meds?

in Finasteride/Dutasteride 10 months ago

The conversation is about experiences with Indian medications for hair loss, specifically using Finax (finasteride), Minopep Gold (minoxidil), and Biotin Plus tablets. Users discuss side effects like low libido and hair regrowth results, with some switching to different brands or dosages to manage side effects.

community Hair growth and natural remedies? Are they worth of it ..

in Treatment 1 upvotes 1 year ago

The user discusses using Minoxidil and plans to start Finasteride for genetic hair loss. They also mention natural remedies like gold shilajit, moringa powder, a seed mixture, and cardio exercise, emphasizing that while these can help, Minoxidil and Finasteride are necessary.

community How much oral minoxidil is satisfactory?

in Minoxidil 6 upvotes 1 year ago

A user taking 1.25mg finasteride and 2.5mg oral minoxidil for hair loss, questioning if the dosage is enough for scalp hair regrowth. Another user reassures that hair will regrow stronger after initial shedding.

community 1mg and .5mg finasteride inhibit roughly the same amount of DHT, but have studies ever directly compared the two when just looking at regrowth?

in Finasteride/Dutasteride 12 upvotes 1 year ago

The conversation is about whether taking 0.5mg of finasteride daily is as effective as 1mg for hair regrowth and if there are long-term studies supporting the lower dose. The user is considering the lower dose to save money and reduce concerns about side effects.

community 5ar alpha reductase stimulation is different depending on whether it’s type 1 or 2

in Hair Systems 16 upvotes 2 years ago

The conversation discusses how different factors can stimulate type 1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.

Similar Research

5 / 1000+ results

Nanotechnology-Based Techniques for Hair Follicle Regeneration

research Nanotechnology-Based Techniques for Hair Follicle Regeneration

October 2023 in “Biomaterials”

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing

research Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing

2 citations , June 2023 in “Pharmaceutics”

Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.

research Nanotechnology Approaches in Chronic Wound Healing

110 citations , April 2020 in “Advances in Wound Care”

Nanotechnology shows promise for better chronic wound healing but needs more research.

Functional Skin Grafts: Where Biomaterials Meet Stem Cells

research Functional Skin Grafts: Where Biomaterials Meet Stem Cells

43 citations , July 2019 in “Stem Cells International”

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?

133 citations , July 2020 in “Cells”

Creating fully functional artificial skin for chronic wounds is still very challenging.