Gold Nanoparticle/Silk Fibroin-Based Nanofiber Enhances Skin Regeneration

June 2025 in “ Journal of Pharmacy and Pharmacology ”

Ozan Özcan, Elif Tufan, Aleyna Muhan, Esın Ak, Göksel Şener, Tuğba Tunalı Akbay

gold nanoparticles silk fibroin nanofiber wound healing hair follicle formation re-epithelialization

TLDR Gold nanoparticles with silk fibroin improve wound healing better than silk fibroin alone.

The study investigated the wound-healing potential of gold nanoparticles combined with silk fibroin-based nanofiber using a green chemistry approach. Conducted on 40 rats divided into two treatment periods (7 and 21 days), the research compared control, silver, silk fibroin, and silk + gold nanoparticle groups. Results showed that the gold nanoparticle/silk fibroin-based nanofiber effectively restored skin damage indicators to normal levels and promoted hair follicle formation and re-epithelialization at the wound site. The study concluded that the addition of gold nanoparticles to silk fibroin significantly enhanced wound-healing properties compared to silk fibroin alone.

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Gold Nanoparticle/Silk Fibroin-Based Nanofiber Enhances Skin Regeneration

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research Wound Healing: A Cellular Perspective

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