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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Some medicinal plants can help heal wounds and may lead to new treatments.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Aging causes skin stem cells to work less effectively.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Oxidative stress contributes to hair graying and loss as we age.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.