Multiplex Matrix Network Analysis of Protein Complexes in the Human TCR Signalosome

    August 2016 in “ Science Signaling ”
    Stephen Smith, Steven C. Neier, Brendan Reed … Adam G. Schrum
    Studysummary This study developed PiSCES biosignatures that distinguished alopecia areata patients from controls, revealing enhanced basal TCR signaling and a potential disease-specific signaling network signature.
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    Research cited in this study 2

    1. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    2. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010