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This study found that infused mouse epidermal growth factor induced wool follicle involution through a quasi-physiological process similar to catagen and a separate pathological action, resulting in fleece 'break' or shedding.

This review discusses environmental epigenomics and its potential impact on gene regulation and phenotypic outcomes, using the Avy mouse model to illustrate nutritional and environmental effects on the fetal epigenome without presenting new findings.

This collection reviews various animal models for dermatological research, particularly focusing on genetic mutations in laboratory mice, and reports no original findings.

This study found that homozygous mutant mice with a hypomorphic CD18 mutation developed a chronic inflammatory skin disease resembling human psoriasis, potentially implicating additional genetic factors in disease susceptibility.

This study found that local injections of interleukin-4 and neutralizing anti-interferon-γ antibody effectively treated alopecia in a mouse model, suggesting potential therapeutic pathways for human alopecia areata.

This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.

This study found that grafting split-thickness human skin onto nude mice produces scars that mimic hypertrophic scar characteristics in humans, offering a useful model for studying scar formation and treatments.

A missing mK6irs1 gene causes hair loss in mice.

This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.

This study found that in rodent diabetes models, measuring corticosterone levels in new growth hair was more sensitive to hyperglycemia-induced changes than using old hair or serum samples.

This study demonstrated that quercetin effectively treated alopecia areata and prevented its onset in a mouse model, suggesting potential for clinical applications in managing the condition.

This study established a mouse model for Cushing's syndrome due to a specific Crh mutation, which may help explore the effects of glucocorticoid excess and evaluate treatments for corticosteroid-induced osteoporosis.

This study created a humanized mouse model of hereditary vitamin D-resistant rickets that lacks alopecia, indicating the mutant receptor's potential to explore the syndrome's characteristics beyond vitamin D binding.

This study demonstrated that human sebaceous glands can be successfully transplanted onto nude mice, where androgen stimulation increases gland volume, cell size, and labeling index.

This study found that recombinant hepatitis B vaccine may increase the risk of alopecia areata onset in older predisposed mice but larger trials suggest this effect might lie within normal variation.

This study describes a mouse model for Marie Unna Hereditary Hypotrichosis, identifying mutations in the hairless gene that result in sparse or absent hair and cyst-like hair follicles.

This study reported that heat treatment significantly increased the incidence of alopecia areata in C3H/HeJ mice, suggesting a role for induced HSPA1A/B expression in disease development.

This study reports that the transgenic expression of Dsg1 in mice rescued the severe B6-Dsg3−/− phenotype and created a syngeneic mouse model of pemphigus vulgaris, which may aid in understanding autoimmunity mechanisms.

In this review, researchers discussed recent insights into caspases, enzymes initially associated with cell death and inflammation, revealing their broader roles in cell proliferation, migration, and differentiation, and highlighting the importance of caspase knock-out mice for understanding their implications in diseases.

This article describes a preliminary study on the effects of topically applied minoxidil on hair growth in Skh-hairless-1 mice, but reports no new results.

This study developed a mouse model to simulate chronic radiation-induced salivary dysfunction, revealing dose-dependent saliva reduction and glandular changes, which may help advance salivary regenerative therapies.

Harris et al. describe a new mouse model for vitiligo, where interfollicular melanocytes are retained and melanocyte-targeting immune responses are simulated, aiding the development of immunomodulatory therapies.

This study successfully created a mouse model with conditional knockout of the p75 neurotrophin receptor gene in epidermis cells, with no significant changes in skin histomorphology observed.

This study developed a pemphigus model in mice showing that anti-Desmocollin 3 and anti-Desmoglein 3 antibodies lead to more severe disease, suggesting diverse antigens contribute to varying human pemphigus phenotypes.

In this study, researchers developed a pemphigus mouse model expressing anti-Desmocollin 3 antibodies and found it mimicked atypical pemphigus with distinct pathological features compared to the standard Desmoglein 3 model.

This study found that cyclosporine A stimulates hair growth in a mouse model by preventing catagen development and increasing expression of certain growth factors.

This study reviews the development of a mouse model using pyroxylin to induce localized hair growth and shorten the hair cycle's resting phase, suggesting it as a platform for evaluating hair growth treatments, though further research is needed for human application.

This study developed a testosterone propionate-induced C57BL/6 mouse model of androgenetic alopecia, demonstrating that high-dose, prolonged testosterone administration inhibited hair regrowth and mirrored human AGA pathology, providing a useful platform for studying hair loss mechanisms and testing therapies targeting the Wnt/β-catenin pathway.

In a testosterone-induced mouse model, this study found that exosomes from injectable Platelet-Rich Fibrin (i-PRF) significantly reduced inflammation, oxidative stress, and apoptosis, while enhancing hair regeneration, with the greatest improvements seen when combined with minoxidil, suggesting potential as a novel treatment for androgenetic alopecia.

This study examined a mouse model of androgenetic alopecia and found that treatment with PRP-exosomes, alone or in combination with minoxidil, led to improved hair growth and reduced IL-6 expression compared to controls.