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    An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

    December 2013 in “ Endocrinology
    Liz Bentley, Christopher T. Esapa, M. Andrew Nesbit … Rajesh V. Thakker
    Studysummary This study established a mouse model for Cushing's syndrome due to a specific Crh mutation, which may help explore the effects of glucocorticoid excess and evaluate treatments for corticosteroid-induced osteoporosis.
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