Cutaneous Transcriptome Analysis in NIH Hairless Mice

    August 2017 in “ PloS one ”
    Zhong-Hao Ji, Jian Chen, Wei Gao … Wenzhi Ren
    Studysummary This study found that NIH hairless mice exhibit abnormalities in hair growth and immune-related pathways, with Pik3r1 and Pik3r3 identified as key genes for further investigation.
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    Research cited in this study 6

    1. Differential Expression of Proteins Associated with the Hair Follicle Cycle: Proteomics and Bioinformatics Analyses PLOS ONE · 2016
    2. Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia PLoS ONE · 2013
    3. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update Journal of Dermatological Science · 2012
    4. A Novel Mutation in Hr Causes Abnormal Hair Follicle Morphogenesis in Hairpoor Mouse, an Animal Model for Marie Unna Hereditary Hypotrichosis Mammalian genome · 2009
    5. The Near-Naked Hairless Mutation Disrupts Hair Formation but Is Not Due to a Mutation in the Hairless Coding Region ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    6. A Novel Missense Mutation in the Mouse Hairless Gene Causes Irreversible Hair Loss: Genetic and Molecular Analyses of Hrm1Enu Genomics · 2006

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