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    Glossary Hedgehog signaling pathway

    regulates cell growth and development through protein-receptor interactions

    The Hedgehog signaling pathway is a crucial mechanism in developmental biology that regulates cell growth, differentiation, and tissue patterning. It involves the Hedgehog proteins binding to receptors on cell surfaces, which then trigger a cascade of intracellular events that influence gene expression. This pathway is essential for proper embryonic development and, when dysregulated, can lead to conditions such as cancer and congenital disorders.

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    1. Conditional Disruption of Hedgehog Signaling Pathway Defines its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000 · 194 citations
    2. Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2005 · 113 citations
    3. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017 · 72 citations
    4. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    5. Exosomes Derived From Human Adipose-Derived Stem Cells Inhibit Lipogenesis Involving Hedgehog Signaling Pathway Frontiers in Bioengineering and Biotechnology · 2021 · 13 citations
    6. Vitamin E promotes dermal papilla cell proliferation via the lncRNA2919/STAT1 axis to activate the Hedgehog signaling pathway Non-coding RNA Research · 2026
    7. Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology International journal of dermatology and venereology · 2019
    8. Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways Frontiers in pharmacology · 2018 · 14 citations
    9. Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems Queen Mary Research Online (Queen Mary University of London) · 2007
    10. Abstract CN06-04: The hedgehog signaling pathway in cancer. Molecular Cancer Therapeutics · 2011
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