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    Glossary Indian Hedgehog

    signaling protein crucial for hair follicle development and cycling

    Indian Hedgehog (Ihh) is a signaling protein that plays a crucial role in the regulation of embryonic development, including the formation of hair follicles. It is part of the Hedgehog signaling pathway, which is essential for cell differentiation and tissue patterning. In the context of hair biology, Ihh influences the growth and cycling of hair follicles, and disruptions in this pathway can lead to conditions like alopecia.

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    Research 10 of 1000+

    1. An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis Development · 2004 · 99 citations
    2. Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects against Malignant Progression Cell Reports · 2013 · 15 citations
    3. The effects of sonic, desert and Indian hedgehog signalling in skin 2003
    4. Developmental signals in skin morphogenesis Experimental Dermatology · 2004
    5. Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2005 · 113 citations
    6. Evaluation of the Tolerability of Hedgehog Pathway Inhibitors in the Treatment of Advanced Basal Cell Carcinoma: A Narrative Review of Treatment Strategies American Journal of Clinical Dermatology · 2024 · 10 citations
    7. Sonic Hedgehog signalling in the regulation of barrier tissue homeostasis and inflammation FEBS Journal · 2021 · 23 citations
    8. Molecular Signaling and Nutritional Regulation in the Context of Poultry Feather Growth and Regeneration Frontiers in Physiology · 2020 · 4 citations
    9. Abstract CN06-04: The hedgehog signaling pathway in cancer. Molecular Cancer Therapeutics · 2011
    10. MicroRNA-mediated regulation of hair follicle regeneration: mechanisms, delivery strategies, and translational perspectives Frontiers in Cell and Developmental Biology · 2026
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