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    Glossary Hedgehog Proteins

    regulate tissue growth and development through signaling pathways

    Hedgehog Proteins (Hh Proteins) are a group of signaling molecules that play a crucial role in regulating the growth and development of various tissues and organs in the body. They are essential for processes such as cell differentiation, tissue patterning, and the maintenance of stem cells. In the context of hair biology, Hedgehog signaling is important for hair follicle development and cycling, and disruptions in this pathway can contribute to conditions like alopecia.

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    1. Hair growth-promoting effect of recombinant human sonic hedgehog proteins Biomedical dermatology · 2019 · 3 citations
    2. Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways Frontiers in pharmacology · 2018 · 14 citations
    3. LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling Cellular Signalling · 2020 · 11 citations
    4. Hedgehog and Gli Signaling in Embryonic Mammary Gland Development Journal of mammary gland biology and neoplasia · 2013 · 25 citations
    5. Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity Cancer Research · 2006 · 70 citations
    6. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state Developmental cell · 2022 · 25 citations
    7. Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity 2023
    8. Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity 2023
    9. GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells 2008 · 39 citations
    10. Single-cell analysis of basal cell carcinoma reveals heat shock proteins promote tumor growth in response to WNT5A-mediated inflammatory signals bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 1 citations
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    1. Physio-metabolic method (antiandrogen, minoxidil, leg training and cold) Community · 7 Jun 2024
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