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An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

27 citations , December 2013 in “Endocrinology”

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor

December 2016 in “Springer eBooks”

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

research Gonadal Function in Men with Cushing Syndrome

January 2013 in “Journal of Endocrinology and Diabetes Mellitus”

Cushing syndrome often causes low testosterone and sexual issues in men.

research Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications

38 citations , January 2014 in “International Journal of Endocrinology”

Adrenal disorders can cause lasting brain and behavior issues in children.

research Gonadal Function in Men with Cushing Syndrome

1 citations , November 2013

Men with low testosterone or breast growth should be checked for Cushing syndrome.

View more "glucocorticoid excess" in research →

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community AA and Hirsutism but T levels are normal

in Female 6 upvotes 4 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 1 year ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community No luck with meds, Check your Cortisol.

in Treatment 36 upvotes 1 year ago

Cortisol from stress can cause hair loss. Controlling cortisol levels improved the effectiveness of finasteride for hair regrowth.

community NootBro Recommendations… How Do We Feel

in Research/Science 9 upvotes 1 year ago

The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.