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    Glossary NR3C1 gene

    encodes a receptor for stress hormones like cortisol

    The NR3C1 gene, also known as the Glucocorticoid Receptor Gene, encodes a protein that binds to glucocorticoids, which are hormones involved in regulating metabolism, immune response, and stress. This gene plays a crucial role in how the body responds to stress and inflammation, and mutations or variations in NR3C1 can impact conditions like depression, anxiety, and autoimmune diseases.

    Research 10 of 78

    1. Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes Hormones · 2017 · 15 citations
    2. Recent advances in the molecular mechanisms causing primary generalized glucocorticoid resistance Hormones · 2016 · 15 citations
    3. The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene JCEM case reports · 2023
    4. Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor Springer eBooks · 2016
    5. Chrousos syndrome: from molecular pathogenesis to therapeutic management European Journal of Clinical Investigation · 2015 · 47 citations
    6. Diagnostic approach to low‐renin hypertension Clinical Endocrinology · 2018 · 29 citations
    7. Glucocorticoid Resistance Syndrome in 2 Patients With Diverse Genotype JCEM Case Reports · 2025
    8. LBODP010 A Case of Glucocorticoid Resistance Syndrome Journal of the Endocrine Society · 2022
    9. 479 Transcriptomics identifies potential novel therapeutic targets in androgenetic alopecia Journal of Investigative Dermatology · 2017
    10. Dimorphic regulation of the MafB gene by sex steroids in hamsters (Mesocricetus auratus) Research Square (Research Square) · 2024
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