Search
for

    Glossary NR3C1 gene

    encodes a receptor for stress hormones like cortisol

    The NR3C1 gene, also known as the Glucocorticoid Receptor Gene, encodes a protein that binds to glucocorticoids, which are hormones involved in regulating metabolism, immune response, and stress. This gene plays a crucial role in how the body responds to stress and inflammation, and mutations or variations in NR3C1 can impact conditions like depression, anxiety, and autoimmune diseases.

    Sort by

    Research 30 of 67

    1. Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes Hormones · 2017 · 15 citations
    2. Recent advances in the molecular mechanisms causing primary generalized glucocorticoid resistance Hormones · 2016 · 15 citations
    3. The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene JCEM case reports · 2023
    4. Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor Springer eBooks · 2016
    5. Chrousos syndrome: from molecular pathogenesis to therapeutic management European Journal of Clinical Investigation · 2015 · 47 citations
    6. Diagnostic approach to low‐renin hypertension Clinical Endocrinology · 2018 · 29 citations
    7. Glucocorticoid Resistance Syndrome in 2 Patients With Diverse Genotype JCEM Case Reports · 2025
    8. LBODP010 A Case of Glucocorticoid Resistance Syndrome Journal of the Endocrine Society · 2022
    9. 479 Transcriptomics identifies potential novel therapeutic targets in androgenetic alopecia Journal of Investigative Dermatology · 2017
    10. Associations between genetically predicted sex and growth hormones and facial aging in the UK Biobank: a two−sample Mendelian randomization study Frontiers in endocrinology · 2023 · 1 citations
    11. Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor BMC Endocrine Disorders · 2014 · 62 citations
    12. Effect of inhibiting prolactin secretion on secondary hair follicle development in cashmere goats Animal Bioscience · 2025
    13. TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells Research Square (Research Square) · 2023
    14. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men Cell Stem Cell · 2020 · 139 citations
    15. Transcriptional Profiling in Rat Hair Follicles following Simulated Blast Insult: A New Diagnostic Tool for Traumatic Brain Injury PLoS ONE · 2014 · 10 citations
    16. 476 Development of an intrinsic skin sensor for blood glucose level with CRISPR-mediated genome editing in epidermal stem cells Journal of Investigative Dermatology · 2017
    17. Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging Scientific Reports · 2021 · 12 citations
    18. Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia Medicina-lithuania · 2023
    19. Pharmacovigilance profiles of three generations of mineralocorticoid receptor antagonists and network toxicology analysis Frontiers in Medicine · 2026
    20. In Silico Promoter Motif Analysis of Human Fertility-Related Genes Applied Biosciences · 2026
    21. GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states PLOS Genetics · 2017 · 38 citations
    22. PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery Journal of Chemical Information and Modeling · 2024 · 110 citations
    23. 26-SNP Panel Aids Guiding Androgenetic Alopecia Therapy and Provides Insight into Mechanisms of Action Cosmetics · 2025
    24. Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats Cells · 2023
    25. Adrenal causes of endocrine hypertension in childhood or adolescence Journal of Endocrinological Investigation · 2025
    26. Transcriptomic analyses of regenerating adult feathers in chicken BMC Genomics · 2015 · 45 citations
    27. Two-Stage Machine Learning-Based GWAS for Wool Traits in Central Anatolian Merino Sheep Agriculture · 2025
    28. Metabolic dysfunction in female mice with disruption of 5α-reductase 1 2017 · 11 citations
    29. Exploring the mechanism of stigmasterol against androgenetic alopecia using geometry optimization, network pharmacology, molecular docking, and molecular dynamics studies Scientific Reports · 2026
    30. Development and evaluation of animal models for sex steroid deficient dry eye Journal of Pharmacological and Toxicological Methods · 2014 · 18 citations