Pathophysiological Mechanisms Implicated in Postpartum Depression

    January 2019 in “ Frontiers in Neuroendocrinology ”
    Jennifer L. Payne, Jamie Maguire
    Studysummary This review summarizes proposed pathophysiological mechanisms of postpartum depression, highlighting neuroendocrine and neurobiological changes, but reports no new findings and calls for integrated understanding of the disorder.
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    Research cited in this study 2

    1. Changes in Expression and Function of Extrasynaptic GABA A Receptors in the Rat Hippocampus During Pregnancy and After Delivery Journal of Neuroscience · 2009
    2. Inhibition of Progesterone Metabolism Mimics the Effect of Progesterone Withdrawal on Forced Swim Test Immobility Pharmacology Biochemistry and Behavior · 2007