Reversal of Alopecia Areata in a Mouse Model of Human Hair Loss by Daily Dietary Administration of a Proprietary Extract of North American Ginseng (Panax Quinquefolius)
January 2015
TLDR North American ginseng extract helped regrow hair in balding mice.
In a 2015 study, researchers found that a proprietary extract of North American ginseng (CVT-E002) induced significant hair regrowth in a mouse model of alopecia areata. The study involved 14 elderly alopecic C3H mice, which were fed 80 mg of CVT-E002 daily for 32 weeks, leading to complete hair regrowth. The regrowth was maintained for an additional 14 weeks even after the extract was removed from the diet. A lower dose of 2 mg per day resulted in a slower onset of hair regrowth. The treatment also increased the number of natural killer (NK) cells and non-NK T/B lymphocytes in the spleen, bone marrow, and blood, suggesting an immunomodulatory effect. The study, sponsored by Afexa Life Sciences, Inc., indicates that CVT-E002 may help in treating alopecia areata by affecting immune cell numbers and functions.
