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Glossary Lymphocytes

type of white blood cell crucial for immune defense

Lymphocytes are a type of white blood cell that play a crucial role in the immune system by helping the body fight off infections and diseases. There are two main types: B cells, which produce antibodies to neutralize pathogens, and T cells, which destroy infected cells and coordinate the immune response.

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Research

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research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia

38 citations , January 2016 in “Cell Death and Disease”

This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.

research Follicular mycosis fungoides mimicking a cutaneous B‐cell lymphoproliferative disorder

14 citations , July 2004 in “Australasian Journal of Dermatology”

This case study describes a patient with rapidly progressing follicular mycosis fungoides, highlighting its unusual histology and challenges in diagnosing it against cutaneous B-cell lymphoma.

research Canine and Feline Cutaneous Lymphocytosis: Reactive Process or Indolent Neoplastic Disease?

1 citations , December 2021

This study concluded that cutaneous lymphocytosis in cats appears to have a reactive nature with prolonged survival, while in dogs, it is more variable with clonality differences and treatment response.

research Clinical, morphological and immunohistochemical characterization of cutaneous lymphocytosis in 23 cats

35 citations , February 2004 in “Veterinary Dermatology”

This study observed that cutaneous lymphocytosis in cats is a slowly progressive and relatively benign disease, but predicting individual clinical outcomes from skin lesions was not possible.

research Functional interrogation of lymphocyte subsets in alopecia areata using single-cell RNA sequencing

23 citations , July 2023 in “Proceedings of the National Academy of Sciences”

In this study using a mouse model and human data, researchers found that CD8+ T cells are central to driving alopecia areata, while regulatory T cells offer some protection, highlighting CD8+ T cells as key targets for future therapy development.

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Community Join

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Potential role of TB-500 Thymosin Beta-4

7 upvotes 1 year ago

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, RU58841, and TB-500 Thymosin Beta-4. It critiques the credibility of biohacking claims.

community Transplant done in 2022. Was on Finas on & off till May 2025. Due to lymph node TB had to stop it.

17 upvotes 1 week ago

The user had a hair transplant in 2022 and stopped using finasteride due to lymph node tuberculosis, expressing concerns about restarting it. They are considering alternatives like PRP and topical treatments but are hesitant about minoxidil due to past hair loss experiences.

community Trialing the probiotics BB536, PTA 6475 so you don’t have to

75 upvotes 1 year ago

Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

community What about cofactor NADPH ? Why don't we ever talk about it ?

11 upvotes 2 years ago

The conversation discusses the role of NADPH in hair loss and the potential impact of creatine and B complex vitamins on hair shedding. The user theorizes that increasing NAD levels with B complex vitamins may reduce hair shedding, despite using finasteride and minoxidil for 9 months.

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Learn

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learn Scalp Micropigmentation

Will scalp micropigmentation work with gray hair? Providers say SMP can be matched to gray hair using lighter or gray-scale pigments. Dark pigment can contrast with white hair and may need adjusting at touch-ups.

learn Thymosin Beta 4

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